Digestly

Mar 18, 2025

I Tried a $30,000 Cure for Depression

Bryan Johnson - I Tried a $30,000 Cure for Depression

The Saint Protocol offers a promising alternative for treating depression, especially for those resistant to traditional treatments. It uses Transcranial Magnetic Stimulation (TMS) to target specific brain areas linked to depression. The treatment is non-invasive and has minimal side effects, making it an attractive option for those who have not found relief with medications. However, access can be challenging due to high costs and limited insurance coverage. The protocol involves an intensive schedule of TMS sessions over five days, which some patients find exhausting but ultimately beneficial. Patients report feeling significant improvements in mood and mental clarity, although results can vary. The treatment's success highlights the importance of exploring new methods for mental health care, especially for those who have struggled with conventional therapies.

Key Points:

  • The Saint Protocol is a non-invasive treatment for depression using TMS, with a 79% success rate.
  • It is completed over five days, involving multiple daily sessions, making it more intensive than standard TMS.
  • Access to the treatment can be difficult due to high costs and limited insurance coverage.
  • Patients often experience significant mood improvements, though results can vary.
  • The treatment is particularly beneficial for those with treatment-resistant depression.

Details:

1. 🌟 First Impressions of TMS

  • The sensation experienced during TMS is similar to a tapping feeling, providing a unique tactile experience.
  • Participants receive a countdown of three seconds before the sensation begins, allowing for mental preparation and reducing surprise.
  • The setting and environment during TMS sessions are calm and controlled, which helps participants feel at ease.
  • Many participants report feeling an initial curiosity or apprehension, which is often alleviated by the structured approach of the session.
  • Comparatively, the sensation is less intense than expected by most, leading to a more positive initial experience.

2. πŸ” Introduction to SAINT Protocol

  • The SAINT protocol is a non-invasive and non-drug treatment for depression, achieving a 79% success rate. It represents a significant advancement in mental health treatment by offering an alternative to traditional methods, which often involve medication or invasive procedures.
  • The protocol's high success rate highlights its potential as a breakthrough in treating depression, providing patients with a new option that reduces reliance on pharmaceuticals.
  • Understanding the SAINT protocol's mechanism and application could further enhance its adoption and benefit patients seeking alternative treatments.

3. 🧠 Personal Mental Health Journey

  • The speaker maintains a dual mindset: internally hopeful yet outwardly skeptical about their mental health journey, indicating a complex emotional state that requires ongoing management.
  • They have been co-founding and building a company, Blueprint, for the past four years alongside Brian, reflecting a significant professional commitment that necessitates balancing with personal health.
  • The speaker emphasizes the importance of distinguishing between professional commitments and personal mental health priorities, suggesting strategies for maintaining this balance.
  • External encouragement plays a crucial role in the speaker's mental health journey, underscoring the value of a supportive network in managing mental health challenges.
  • The speaker implies that specific strategies, possibly including regular breaks and mindfulness, are employed to navigate the pressures of entrepreneurship, although these are not detailed in the transcript.

4. πŸšͺ Challenges of Access and Cost

  • In the US, approximately 13% of people are on anti-depressants, with women being twice as likely as men to use them, highlighting a significant need for effective depression treatments.
  • TMS is identified as a recommended first-line treatment for depression due to its effectiveness, yet access remains limited.
  • The out-of-pocket cost for TMS treatment is around $30,000, making it financially inaccessible for many patients.
  • Obtaining insurance coverage for TMS is notably difficult, which exacerbates accessibility issues.
  • Insurance companies often require proof of failure of other treatments before approving TMS, adding a barrier for patients seeking this option.

5. πŸ˜” Physical and Emotional Impact

  • The individual experiences severe physical symptoms such as body seizing up and inability to move, indicating a significant physical response to emotional stress.
  • Wakeup paralysis occurs occasionally, approximately once every one to two weeks, impacting daily functioning and indicating severe emotional distress.
  • The lack of motivation to perform basic functions like urination highlights the depth of emotional and psychological impact.
  • Transcranial Magnetic Stimulation (TMS) is mentioned as a potential treatment, using magnets to activate brain regions associated with mood regulation.
  • TMS could help alleviate symptoms by targeting specific brain areas, offering a non-invasive alternative to medication.

6. πŸ”„ The TMS Treatment Experience

6.1. Standard TMS Treatment

6.2. SAINT Protocol: An Advanced TMS Approach

7. 🎯 Hopes for Broader Accessibility

  • Medicare currently covers this treatment only in a hospital setting, which limits accessibility for many patients who could benefit from home treatment options.
  • The aspiration is for broader insurance coverage by most carriers, which would allow more patients to receive the treatment in a more convenient setting.
  • The speaker expresses feeling fortunate to have access to the treatment, highlighting a motivation to raise awareness and advocate for expanded coverage.
  • There is a significant emotional journey involved, as patients navigate varying perceptions of their struggles and the disparities in access to care.

8. πŸ’­ Confronting Personal Perceptions

  • Depression, affecting a significant portion of the population, sees only 35% of sufferers seeking treatment, primarily due to a lack of recognition of the illness's severity and societal stigma.
  • Despite widespread prevalence, life satisfaction remains low among those affected, with many reporting dissatisfaction in social interactions and cognitive impairments like slowness and reduced well-being.
  • To address these challenges, a company has introduced an innovative algorithm designed to predict responses to Transcranial Magnetic Stimulation (TMS), enhancing the precision of treatment plans and potentially increasing treatment success rates.

9. πŸ—οΈ Insights and Self-Awareness

  • The brain stimulation process aims to enhance insights and self-awareness by determining the precise intensity needed for effective brain engagement.
  • The strategy involves starting with low intensity, gradually increasing until a consistent, comfortable level is reached, emphasizing a tailored approach.
  • Each session includes approximately 60 stimulation trains, indicating a repeated and structured methodology designed for optimal results.
  • Participants describe the sensation as a mix of electricity and tapping, reflecting a unique physical response critical for understanding the experience.
  • Adjustments are made based on participant comfort, ensuring personalization and enhancing the overall effectiveness of the process.
  • The ultimate goal is to achieve a balance between intensity and comfort to maximize the stimulation’s impact on cognitive and emotional awareness.

10. 🎒 Navigating Emotional Highs and Lows

  • The speaker reflects on past experiences where extreme techniques were used for achievements, questioning if current methods will be seen as outdated in the future.
  • Despite achieving global success and fulfilling career goals, the speaker experienced a sense of emptiness and questioned the purpose of everything.
  • Interacting with established systems led to the realization that many are constructed and not inherently meaningful, contributing to feelings of depression.
  • The speaker identified a potential loss of ambition as a factor contributing to their emotional lows.
  • The speaker considers future strategies for maintaining ambition and finding genuine purpose, emphasizing the importance of adapting to change and questioning established norms.

11. πŸ•΅οΈ Embracing Reality and Seeking Help

  • TMS therapy is a non-invasive treatment typically requiring several months, but the Saint Protocol compresses this into an intensive 5-day schedule from 8:00 a.m. to 6:00 p.m. with 10-minute TMS sessions followed by 50-minute breaks.
  • The Saint Protocol offers a potential life-changing impact with minimal side effects, making it a feasible option for many patients.
  • Participants might experience tiredness, nausea, and discomfort due to the rigorous treatment schedule, yet it remains accessible and suitable for diverse patients.
  • Despite potential exhaustion by the 50th session, the treatment's condensed nature provides significant efficiency and effectiveness over traditional methods.
  • While the Saint Protocol's outcomes and success rates aren't detailed, its innovative approach and intensive schedule represent a significant advancement in TMS therapy.

12. ✨ Overcoming Denial

  • The speaker realized that their perception of depression was inaccurate, initially imagining it as a dramatic and visible state, but later understanding it can be subtle and pervasive.
  • Despite feeling depressed, the speaker maintained everyday functions at work and social interactions, which led to a false sense of being okay.
  • Acknowledging the discrepancy between outward appearance and internal feelings was a significant realization for the speaker.
  • The speaker expressed fear of having treatment-resistant depression, highlighting a concern over the permanence of their condition.
  • The speaker emphasized the importance of faith in the treatment process and trusting that improvement is possible, despite current doubts and fears.

13. πŸŒ€ The Intensity of TMS Treatment

  • TMS treatment is used for severe depression cases when other treatments have failed, marking it as a crucial option in mental health care.
  • Patients often experience feelings of undeservedness and impostor syndrome during TMS, underscoring the psychological challenges involved.
  • The Saint Protocol from Stanford University, consisting of around 35 sessions, is an innovative approach designed to regulate brain activity and improve depression symptoms.
  • Family and friend visits during treatment can positively influence patient mood and outlook, providing emotional support that enhances treatment efficacy.
  • Skepticism exists about TMS efficacy, with concerns about individual responses and potential failure, highlighting the need for patient-specific evaluations.
  • Patients report TMS effects as subtle, akin to lifting a persistent weight, indicating gradual mental health improvements.
  • More scientific insights could enhance understanding of the Saint Protocol's expected outcomes, bridging patient experiences with technical details.

14. 🌈 Journey Towards Recovery and Hope

  • Depression was significantly alleviated, leading to improved quality of life and reduced self-destructive behaviors.
  • HIV remained stable, indicating successful health management alongside mental health improvements.
  • Relapses are part of the journey, but overall improvements were noticeable to others.
  • Transcranial Magnetic Stimulation (TMS) was effective in mood improvement, as observed by the individual and others around them.
  • PMS affected mood, but improvements were noted post-cycle, highlighting TMS's effectiveness.
  • Denial of symptoms can delay recovery; recognizing and addressing them early is crucial.
  • Engagement with healthcare professionals and trusted individuals is essential for clarity and support.
  • Immediate action upon symptom recognition aids faster recovery, preventing prolonged depression.
  • Support networks are vital; reaching out to trusted individuals is encouraged.
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