Dr. Mike introduces the concept of Raw Stimulus Magnitude (RSM), which he defines as a measure of how much muscle growth an exercise is likely to stimulate. He explains that RSM is determined by factors such as mind-muscle connection, the pump, perturbation, and disruption. These factors help rank exercises based on their potential to stimulate muscle growth without considering fatigue. Dr. Mike contrasts RSM with the Stimulus to Fatigue Ratio (SFR), which considers both the muscle growth stimulus and the fatigue caused by an exercise. He suggests that RSM is particularly useful for beginners or those with low fatigue constraints, as they can focus on maximizing muscle growth without worrying about fatigue. He provides guidelines for selecting high RSM exercises, such as choosing compound movements, free weights, and exercises with a high range of motion. Dr. Mike also offers a sample workout program using these principles, emphasizing the importance of tailoring exercise selection to individual needs and goals.