The video highlights TikTok Shop as a major opportunity for individuals looking to engage in live shopping and sell items directly to consumers. It suggests that even without a large following, users can leverage TikTok's platform to reach a wide audience by going live and selling items. The speaker provides a practical example of buying inexpensive items from stores like TJ Maxx and reselling them on TikTok Shop for a profit. This process can be repeated to build a sustainable income stream. The emphasis is on the ease of starting this venture, as TikTok's algorithm supports live shopping, allowing sellers to reach potential buyers effectively. This creates a significant arbitrage opportunity for those willing to engage in this form of commerce.